Battling Arthritis

Since I started this blog, there are already 4 posts wherein arthritis drugs were mentioned or discuss. And so in this resource –type entry, I would like to put those arthritis drugs on the spotlight.

ANTI-TNF THERAPY

Anti-TNF drugs are drugs that inhibit the tumor necrosis factor (TNF) thereby preventing chronic inflammatory diseases such as rheumatoid arthritis.

Examples of TNF inhibitors that are currently approved by the FDA to be in the market are the following:

Infliximab (Remicade®)– a product of Centocor Pharmaceuticals. A biologic treatment used for the treatment of plaque psoriasis, rheumatoid arthritis, psoriatic arthritis, Chron’s disease in adults, pediatric Chron’s disease, ulcerative colitis and ankylosing spondylitis.

D2E7 Adalimumab (Humira) – a product of Abbott. A medicine called a Tumor Necrosis Factor (TNF) blocker, used in adults to reduce the signs and symptoms of:

• moderate to severe rheumatoid arthritis (RA) in adults. HUMIRA can be used alone or with methotrexate or with certain other medicines. HUMIRA may prevent further damage to your bones and joints and may help your ability to perform daily activities.
• psoriatic arthritis (PsA). HUMIRA can be used alone or with certain other medicines. HUMIRA may prevent further damage to your bones and joints and may help your ability to perform daily activities.
• ankylosing spondylitis (AS)
• moderate to severe Crohn’s disease (CD) in adults who have not responded well to conventional treatments. HUMIRA is also approved for these adults who have lost response or are unable to tolerate infliximab.

Etanercept (Enbrel®) – a product of Amgen and Wyeth and a biologic oral medication for moderate to severe rheumatoid arthritis (RA), moderate to severe juvenile rheumatoid arthritisJRA), psoriatic arthritis, ankylosing spondylitis (AS) and chronic moderate to severe plaque psoriasis.

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